October 4, 2021 — Antibody levels may wane after 7 months for people who get the Pfizer-BioNTech vaccine, according to a new study published on the bioRxiv preprint server.
In the study, which has not been reviewed or formally published in a medical journal,
The researchers analyzed blood samples from 46 healthy young or middle-aged adults after two doses, and then 6 months after the second dose.
“Our study shows that vaccination with Pfizer-BioNTech induces high levels of neutralizing antibodies against the original vaccine strain, but these levels decrease by about tenfold by seven months,” the researchers told Reuters.
In about half of adults, neutralizing antibodies were undetectable 6 months after the second dose, especially against MERS-CoV variants such as delta, beta and mu.
Reuters noted that neutralizing antibodies is only part of the body’s immune defense against the virus, but it is still “very important” in protecting against infection with the Corona virus.
“These results indicate that administration of a booster dose at approximately 6 to 7 months after the initial immunization is likely to enhance protection,” the study authors wrote.
BioNTech said a new vaccine formulation will likely be needed by mid-2022 to protect against future mutations of the virus, according to financial times.
“this year, [a different vaccine] Ugur Şahin, Managing Director and CEO of BioNTech, told the news outlet, “Ugur Şahin, MD and CEO of BioNTech.
He said the current variants, specifically the delta variant, are more contagious than the original coronavirus strain but not different enough to evade current vaccines. But the new strains may be able to avoid the reinforcers.
“This virus will survive and the virus will adapt more,” Shaheen said. “This is an ongoing development, and this development is just beginning.”